🇨🇭 Swiss Data Privacy & Precision

ELECTRONIC TRIAL MASTER FILE (ETMF) SOFTWARE

eTMF software for clinical trials

oomnia eTMF software by Wemedoo is a digital workspace for storing, managing, and accessing trial master file documents inside one unified Clinical Research Information System (CRIS).

ISO 27001 SOC 2 FDA 21 CFR Part 11 GDPR & HIPAA

Unified data capture

How does oomnia support TMF clinical trials?

oomnia eTMF software is an electronic trial master file solution that centralizes the creation, storage, and control of essential study documents in a secure, role‑based environment. It allows authorized users to find, review, approve, and sign records from one place at any time.

oomnia eTMF software keeps documents structured and aligned with industry standards while enabling sponsors, CROs, and sites to work together in real time through a unified clinical research information system (CRIS).

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CLINICAL DATA

What is oomnia eTMF system used for?

oomnia eTMF is designed to centralize and manage all essential trial documentation within a single, compliant environment.

oomnia eTMF software supports:

  • All trial documentation in one compliant, unified system

  • Remote collaboration and collection

  • Secure, role‑based access for sponsors, CROs, and sites

  • Real‑time visibility into document status and completeness

  • Audits and inspections with full version history and audit trails

  • Real-time streamlining of document review, approval, and e‑signatures

Key Capabilities

Key capabilities of oomnia eTMF software

Key capabilities of oomnia eTMF software
Aspect Modular eClinical systems Unified clinical trial software (oomnia)
System architecture Separate eTMF system requiring integrations with EDC, CTMS, and site systems eTMF within one unified clinical research information system (CRIS)
Document access Files accessed through a standalone portal or shared drives Centralized access within a connected study workspace for all stakeholders
Data & document availability TMF updates rely on manual uploads or scheduled syncing from other systems Real‑time document availability across all modules with no syncing required
TMF structure & metadata Independent filing structure that must be manually aligned with study data Shared metadata model automatically linked to study, site, and subject records
Collaboration & workflows Limited workflow automation; approvals often handled outside the eTMF Built‑in workflows for reviews, approvals, signature routing, and notifications
Integration with study database Requires manual reconciliation and periodic alignment with EDC/CTMS Always in sync with the unified study database, no reconciliation needed
Audit & traceability Audit trails fragmented across systems and file locations Complete, unified audit trail for every action and version change
Security & compliance System‑specific permissions and isolated security controls Encrypted data, role‑based access, unified CRIS‑wide compliance framework (GxP, 21 CFR Part 11, ICH‑GCP); Fully compliant with international and organizational standards
Time & Cost Efficiency Manual system setup for each new study; Higher operational costs due to duplicated workflows and repeated configurations Rapid study setup by reusing eTMF index, roles, and permissions; Lower operational costs due to unified processes and reusable structures

Regulatory Readiness

Compliance and regulatory readiness

oomnia eTMF software is designed to support regulated clinical research environments and aligns with recognized international regulatory and industry standards governing electronic records, document management, and trial master file oversight.

GxP requirements

Supports GxP-aligned document management and quality practices across all study operations

21 CFR Part 11

Fully compatible with 21 CFR Part 11 electronic records and signature requirements

ICH E6 (R2/R3) GCP

Document workflows and TMF structures aligned with ICH E6 (R2/R3) Good Clinical Practice expectations for TMF management

How It Works

How oomnia eTMF works inside a unified clinical trial software?

Instead of functioning as a standalone tool, oomnia eTMF software is integrated within a unified Clinical Research Information System (CRIS). This means:

No disconnected systems for EDC, CTMS, or site collaboration

Fewer manual filing and reconciliation steps

Consistent document structures, metadata, and terminology across studies

Real‑time alignment between operational data and TMF content

Improved TMF completeness through automated, connected workflows

Who This Is For

Who oomnia eTMF management software is for?

oomnia eTMF is designed for:

CROs overseeing complex, multinational clinical trials

Teams transitioning away from fragmented TMF structures

Fast‑growing biotech and emerging pharma

Organizations seeking inspection readiness at all times

Clinical teams aiming to reduce manual document handling

Companies prioritizing real‑time visibility and oversight

Collaborative teams needing secure, role‑based access

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Reduce fragmentation, cut reconciliation cycles, and gain clear, real‑time oversight across your studies.

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Frequently asked questions

What is eTMF software?

eTMF (Electronic Trial Master File) software is a digital system for organizing, storing, and managing all essential clinical trial documents. Wemedoo's oomnia eTMF software ensures real-time inspection readiness, regulatory compliance, and centralized access to trial documentation throughout the entire study lifecycle.

What are the key features of oomnia eTMF software?

oomnia eTMF software includes centralized document storage and archiving, real-time inspection readiness dashboards, role-based access control, automated document workflows, version control, regulatory compliance tracking, data encryption, two-factor authentication, and seamless integration with EDC and CTMS.

How does oomnia eTMF ensure regulatory compliance?

oomnia eTMF software is built to comply with ICH GCP, 21 CFR Part 11, and international regulatory standards. It maintains complete audit trails, enforces document lifecycle management, provides real-time completeness tracking against the TMF Reference Model, and ensures all documents are inspection-ready at any time.

Can oomnia eTMF integrate with other clinical trial systems?

Yes, oomnia eTMF is natively integrated with all other oomnia modules including EDC, CTMS, and RTSM within one unified system. It also supports interoperability with third-party systems through standard APIs and data exchange formats.

What is the benefit of unified eTMF vs standalone eTMF?

A unified eTMF solution like oomnia automatically receives documents and milestone updates from EDC, CTMS, and other modules, eliminating manual uploads and reducing the risk of missing documents. This ensures higher completeness rates and reduces the administrative burden of TMF management.

How is oomnia eTMF software different from other eTMF solutions?

oomnia eTMF software is part of a unified clinical research information system (CRIS), meaning it is not a separate tool that must be synced with EDC or CTMS. Documents, metadata, and operational data stay connected automatically, reducing reconciliation effort and ensuring real‑time TMF accuracy.

How does oomnia eTMF software support multi‑country or multi‑site trials?

oomnia eTMF software supports country‑level and site‑level document structures with clear separation of permissions. Teams can maintain consistent organization while supporting local variations and region‑specific requirements.

Ready to see oomnia eTMF in action?